GENOMIC LANDSCAPE OF ALLELIC IMBALANCE IN PREMALIGNANT ATYPICAL ADENOMATOUS HYPERPLASIAS OF THE LUNGRESEARCH IN CONTEXT

Genomic landscape of allelic imbalance in premalignant atypical adenomatous hyperplasias of the lungResearch in context

Background: Genomic investigation English pads of atypical adenomatous hyperplasia (AAH), the only known precursor lesion to lung adenocarcinomas (LUAD), presents challenges due to the low mutant cell fractions.This necessitates sensitive methods for detection of chromosomal aberrations to better study the role of critical alterations in early lung

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Security-Reliability Tradeoff for Friendly Jammer Assisted User-Pair Selection in the Face of Multiple Eavesdroppers

In this paper, we explore the physical-layer security in a wireless network consisting of multiple user pairs in the face of multiple eavesdroppers, which are deployed by an adversary for tapping the confidential transmissions of the user pairs deliberately.We propose a friendly Logo jammer-assisted user-pair selection (FJaUPS) scheme to improve th

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Computational and structural based approach to identify malignant nonsynonymous single nucleotide polymorphisms associated with CDK4 gene.

Cycline-dependent kinase 4 (CDK4), an enzyme of the cycline dependent or Ser/Thr protein kinase family, plays a role in cell cycle progression (G1 Cooling phase) by phosphorylating a tumor suppressor protein called pRB.Alteration of this enzyme due to missense mutation/ nonsynonymous single nucleotide polymorphisms (nsSNPs) are responsible for vari

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PROK2 / PROKR2 signaling and Kallmann syndrome

Kallmann syndrome (KS) is a developmental disease that associates hypogonadism and a deficiency of the sense of smell.The reproductive phenotype of KS results from the primary interruption of the olfactory, vomeronasal and 5 Piece Queen Slat Panel Bedroom terminal nerve fibers in the frontonasal region, which in turn disrupts the embryonic migratio

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